pentobarbital will lessen the extent or effect of imatinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Mysterious.pentobarbital will minimize the extent or outcome of fentanyl by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Closely. Coadministration of fentanyl with CYP3A4 inducers cou